مقدمه کلی
آزمایشگاه پاتوبیولوژی و ژنتیک آرمین با همکاری مرکز تحقیقات و گوارش و کبد دانشگاه علوم پزشکی بقیه الله و همچنین شبکه هپاتیت ایران در خصوص انواع ویروس های هپاتیت که یکی از دغدغه های حوزه بهداشت و درمان در منظقه می باشد، طرح های متعددی را به انجام رسانده است.
به طور خلاصه، طرح های انجام شده در حوزه بررسی ژنتیکی و ژنوتیپی ویروس های هپاتیت B و C، عوامل فارماکوژنتیکی و بررسی روند درمان بیماران مبتلا به هپاتیت های ویروسی بوده است.
مقالات تخصصی هپاتیت که جزو دستاورد های آزمایشگاه آرمین می باشد به شرح ذیل است :
- A Simple PCR-RFLP Method for Genotyping of IFNL4 rs368234815 Polymorphism in Patients With Chronic Hepatitis C
- The Role of Polymorphisms Near IFNL3 Gene as Predictors of Residual HCV RNA in Buffy Coat after Successful Antiviral Therapy
- The ITPA and C20orf194 Polymorphisms and Hematological Changes During Treatment With Pegylated-Interferon Plus Ribavirin in Patients With Chronic Hepatitis C
- Impact of IFNL4 rs12979860 and rs8099917 polymorphisms on response to Peg-Interferon- α and Ribavirin in patients with congenital bleeding disorder and chronic hepatitis C
- The Prevalence of Hepatitis C Virus Core Amino Acid 70 Substitution and Genotypes of Polymorphisms Near the IFNL3 Gene in Iranian Patients With Chronic Hepatitis C
- The Role of Polymorphisms Near the IL28B Gene on Response to Peg-Interferon and Ribavirin in Thalassemic Patients With Hepatitis C
- The interferon lambda 4 rs368234815 predicts treatment response to pegylated‑interferon alpha and ribavirin in hemophilic patients with chronic hepatitis C
- FULL GENOME ULTRA-DEEP PYROSEQUENCING IDENTIFIES GG-TO-GA HYPERMUTATION AS NOVEL PREDICTOR FOR TREATMENT RESPONSE TO PEGYLATED INTERFERON ALFA-2A IN HBEAG-NEGATIVE CHRONIC HEPATITIS B
- SIGNIFICANCE OF MICRO RNA-122 IN PATIENTS WITH CHRONIC HEPATITIS C ON INTERFERON THERAPY
- The Impact of IFNL4 rs12979860 Polymorphism on Spontaneous Clearance of Hepatitis C; A Case-Control Study
- The rs12979860 and ss469415590 polymorphisms of IFNL4 gene are in strong linkage disequilibrium in Caucasian patients with chronic hepatitis C
- Study of HBsAg escape mutations in chronic hepatitis B patients under treatment with nucleos (t) ide analogues
- Distribution of IL28B Genotypes in Iranian Patients with Chronic Hepatitis C and Healthy Individuals
- Treatment of Chronic Hepatitis C Infection: Update of the Recommendations from Scientific Leader’s Meeting-28th July 2011-Tehran, IR Iran
- Development and Validation of a Simple, Rapid and Inexpensive PCRRFLP Method for Genotyping of Common IL28B Polymorphisms: A Useful Pharmacogenetic Tool for Prediction of Hepatitis C Treatment Response
- Detection of the YMDD Motif Mutations Rate in Chronic Hepatitis B Patients Treated with Lamivudine
- A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms
